Born in Pennsylvania to parents of Italian ancestry, Dr. Orlando Cicilioni is the product of a Jesuit education. He entered into a career in medicine because it was commensurate with not only his personal talents and skills, but also his morals and ethics and desire to extend the healing ministry. In 1988 he was graduated Summa Cum Laude from the University of Scranton, majoring in Biology. Subsequently, he completed his medical degree at Jefferson Medical College of Thomas Jefferson University in Philadelphia, PA in 1992, where he was also graduated with honors.

Upon completion of his education, Dr. Cicilioni moved to Gainesville, FL and completed residencies in both General Surgery and Plastic Surgery at the University of Florida/Shands Hospital.  In 1999 he began his practice in Central Florida, initially practicing in the City of Winter Park, and later establishing Orlando Cosmetic Surgery, LLC in Orlando.  In 2006 he was named Chairman of the Department of Plastic Surgery for the Florida Hospital Seven campuses.  He served in that role and was also a member of multiple quality control & governing committees at Florida Hospital for 10 years while still very active in private practice.

In 2006 he was named Chairman of the Dept. of Plastic Surgery for the Florida Hospital Seven Campuses. He served in that role and was also a member of multiple quality control & governing committees at Florida Hospital for ten years. He addition to his private practice of plastic and reconstructive surgery, he is also actively involved in clinical research and a faculty member for both the Florida State University and University of Central Florida Colleges of Medicine.